Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 181
interventional 163
Observational 16
Registry 2

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 66
Drug|placebo 35
Other 11
Device 8
Behavioral 7
Procedure 6
Dietary Supplement|placebo 5
Drug|Other 4
Device|Procedure 3
Dietary Supplement 3
Behavioral|placebo 2
Behavioral|Dietary Supplement 1
Behavioral|Drug|placebo 1
Behavioral|Other 1
Biological 1
Biological|placebo 1
Device|Dietary Supplement 1
Device|Dietary Supplement|Procedure 1
Device|Drug|Other 1
Diagnostic Test 1
Drug|placebo|Procedure 1
Drug|Procedure 1
Other|placebo 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 35
China 28
NA 13
Korea, Republic of 10
Spain 7
Japan 6
Belgium 5
Hong Kong 5
Netherlands 5
Sweden 5
Germany 4
United Kingdom 4
Brazil 3
Canada 3
Turkey 3
Australia 2
Ireland 2
Italy 2
Russian Federation 2
Singapore 2
Taiwan 2
Thailand 2
Argentina|Belgium|Brazil|Canada|Denmark|France|Germany|Greece|Iceland|Italy|Norway|Romania|Singapore|South Africa|Spain|Sweden|Switzerland 1
Belgium|Bulgaria|Latvia|Lithuania|Romania|Russian Federation|Slovakia|Sweden|Ukraine|United Kingdom 1
Denmark 1
Egypt 1
Finland 1
France 1
France|Austria|Belgium|Canada|Finland|Germany|Hungary|Mexico|Norway|South Africa|Sweden|Switzerland|United Kingdom 1
Indonesia 1
Iran, Islamic Republic of 1
Mexico 1
Pakistan 1
Poland 1
United States|Canada 1

Sites per Study

Site_count Study_Count
1 136
2 7
3 1
4 1
5 3
6 2
8 1
10 1
12 1
13 1
14 1
20 1
32 1
36 1
46 1
55 1
59 1
182 1
217 1

Phase

Phase Study_Count
N/A 62
Phase 3 39
Phase 4 29
Phase 2 16
Phase 1 6
Phase 2/Phase 3 6
Phase 1/Phase 2 4
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 19
2 84
3 13
4 11
5 1
6 4
NA 31

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 50 7.0000 24.00 20.00 13.0000 24.00 24.0000 66.0000
1st Qu. 50 31.2500 41.25 50.00 40.0000 83.75 115.5000 120.0000
Median 50 64.5000 45.00 67.50 62.5000 147.50 300.0000 161.0000
Mean 50 111.7097 47.50 134.75 137.5625 198.50 413.7436 231.4138
3rd Qu. 50 150.0000 49.50 152.25 183.0000 269.00 478.0000 329.0000
Max. 50 720.0000 80.00 384.00 440.0000 500.00 1500.0000 612.0000

Trial Group Type

group_type Group_Count
Experimental 147
Active Comparator 72
Placebo Comparator 61
NA 31
Other 10
No Intervention 5
Sham Comparator 4

Intervention Model

intervention_model Study_Count
Parallel Assignment 108
Single Group Assignment 32
Crossover Assignment 16
Factorial Assignment 6
Sequential Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 121
Diagnostic 15
Basic Science 11
Supportive Care 4
Other 3
Prevention 3
NA 3
Health Services Research 2
Device Feasibility 1

Observational Studies

Studies by Country

Country Study_Count
United States 6
NA 3
Italy 2
France 1
Germany 1
Indonesia 1
Korea, Republic of 1
Switzerland 1

Sites per Study

Site_count Study_Count
1 16

Enrollment Metrics

Measure Observational
Min 10.000
1st Qu 41.500
Median 79.500
Mean 1033.562
3rd Qu 145.250
Max 14965.000

Observation Model

observational_model Study_Count
Cohort 8
Case-Only 2
Case Control 2
NA 2
Case-Control 1
Case-Crossover 1

Time Perspective

time_perspective Study_Count
Prospective 13
Cross-Sectional 1
Cross-Sectional, Prospective 1
Retrospective 1

Registries

Studies by Country

Country Study_Count
Canada|Iran, Islamic Republic of|Japan 1
United States 1

Sites per Study

Site_count Study_Count
1 1
3 1

Enrollment Metrics

Measure Registries
Min 200
1st Qu 525
Median 850
Mean 850
3rd Qu 1175
Max 1500

Registry Model

observational_model Study_Count
Case-Control 1
Cohort 1

Time Perspective

time_perspective Study_Count
Prospective 2

Follow-up

target_duration Study_Count
1 Day 1
1 Year 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03825692 International Clinical Study of Zhizhu Kuanzhong Capsule https://ClinicalTrials.gov/show/NCT03825692 Enrolling by invitation Xiyuan Hospital of China Academy of Chinese Medical Sciences 2021-12-31
NCT03617016 Preliminarily Evaluate the Efficacy of Domperidone in Adult Chinese Participants With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03617016 Recruiting Xian-Janssen Pharmaceutical Ltd. 2020-07-31
NCT03444831 Buspirone Plus Omeprazole for Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03444831 Completed Isfahan University of Medical Sciences 2017-03-01
NCT03252743 ICBT for Pain-predominant FGIDs in Children and Adolescents: an Implementation Study. https://ClinicalTrials.gov/show/NCT03252743 Completed Karolinska Institutet 2018-06-17
NCT03225248 Efficacy and Safety of UI05MSP015CT in Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03225248 Completed Korea United Pharm. Inc. 2015-09-05
NCT03207516 Sourdough Bakery Products and Digestive Function https://ClinicalTrials.gov/show/NCT03207516 Completed Irccs Sdn 2015-04-28
NCT03205319 Trial to Reduce Inappropriate Oesophagogastroduodenoscopies for Dyspepsia https://ClinicalTrials.gov/show/NCT03205319 Completed Radboud University 2019-03-01
NCT03198507 ERADICATE Hp2 - Treating Helicobacter Pylori With RHB-105 Compared to Active Comparator https://ClinicalTrials.gov/show/NCT03198507 Completed RedHill Biopharma Limited 2018-10-24
NCT03184402 Efficacy and Safety of DWJ1252 in the Treatment of Functional Dyspepsia (PART 2) https://ClinicalTrials.gov/show/NCT03184402 Completed Daewoong Pharmaceutical Co. LTD. 2017-07-31
NCT03176927 Biomagnetic Characterization of Gastric Dysrhythmias III https://ClinicalTrials.gov/show/NCT03176927 Enrolling by invitation Vanderbilt University Medical Center 2020-08-31
NCT03149393 Clinical Study on Post Evaluation After Listing of Qizhi Weitong Granules https://ClinicalTrials.gov/show/NCT03149393 Recruiting Xiyuan Hospital of China Academy of Chinese Medical Sciences 2020-12-31
NCT03078634 The Multi-disciplinary Treatment of Functional Gut Disorders Study https://ClinicalTrials.gov/show/NCT03078634 Active, not recruiting St Vincent’s Hospital Melbourne 2019-02-28
NCT03043625 Visceral Manipulation Treatment to Patients With Non-specific Neck Pain With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03043625 Completed University of Nove de Julho 2017-01-30
NCT01737840 Comparison of Pantoprazole and Ranitidine in Dyspepsia https://ClinicalTrials.gov/show/NCT01737840 Completed Akdeniz University 2013-01-31
NCT03024086 Efficacy and Safety of DWJ1252 in the Treatment of Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03024086 Completed Daewoong Pharmaceutical Co. LTD. 2017-04-25
NCT03007433 Assessment of GI Function to a Large Test Meal by Non-invasive Imaging https://ClinicalTrials.gov/show/NCT03007433 Completed Nottingham University Hospitals NHS Trust 2012-02-29
NCT03003234 Association Between Luminal Bile Salt Content and Duodenal Mucosal Integrity in Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03003234 Completed Universitaire Ziekenhuizen Leuven 2016-11-30
NCT02996604 Acupuncture for Functional Dyspepsia: a Functional Magnetic Resonance Imaging (fMRI) Study https://ClinicalTrials.gov/show/NCT02996604 Completed Chengdu University of Traditional Chinese Medicine 2017-12-31
NCT02956187 Treatment of Constipation in Functional Dyspepsia https://ClinicalTrials.gov/show/NCT02956187 Completed Hospital Universitari Vall d’Hebron Research Institute 2017-12-10
NCT02775591 Effect of Short-term Motilitone Therapy on Health-related Quality of Life in PD Patients With Gastrointestinal Symptoms https://ClinicalTrials.gov/show/NCT02775591 Completed Seoul National University Hospital 2018-06-30
NCT02727556 Physiological Response and Visual Attention to Visual Food Images in Healthy Subjects and in Functional Dyspepsia Patients https://ClinicalTrials.gov/show/NCT02727556 Completed University Hospital Tuebingen 2017-04-30
NCT02685150 Endoscopic Tri-Modal Imaging to Distinguish Functional Dyspepsia From Reflux Disease https://ClinicalTrials.gov/show/NCT02685150 Completed Chinese PLA General Hospital 2018-06-30
NCT02660372 Efficacy and Safety of Two Simeticone Brands in Adults With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT02660372 Completed Johnson & Johnson Consumer and Personal Products Worldwide 2016-10-31
NCT02633930 Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Clarithromycin Quadruple Therapy https://ClinicalTrials.gov/show/NCT02633930 Completed Xijing Hospital of Digestive Diseases 2016-06-30
NCT02621359 A Two Week Nitazoxanidebased Quadruple Regimen https://ClinicalTrials.gov/show/NCT02621359 Recruiting Tanta University 2022-12-31
NCT02620696 Effect of Netazepide on Omeprazole-induced Changes in Chromogranin A and Gastrin https://ClinicalTrials.gov/show/NCT02620696 Completed Trio Medicines Ltd. 2010-09-30
NCT02618070 Cognitive Modulation of Dyspeptic Symptom During Food Ingestion in Functional Dyspepsia Patients Cognitive Modulation https://ClinicalTrials.gov/show/NCT02618070 Completed University Hospital Tuebingen 2017-04-30
NCT02592239 Hedonic Perception and Brain Activity Response to Meal https://ClinicalTrials.gov/show/NCT02592239 Completed Hospital Universitari Vall d’Hebron Research Institute 2017-06-30
NCT02566876 Bifidobacteria In Children With Abdominal Pain-Associated Functional Gastrointestinal Disorders https://ClinicalTrials.gov/show/NCT02566876 Completed Federico II University 2015-07-31
NCT02498041 The Efficacy and Patient Tolerance of Ultrathin Nasal Endoscopy to Detect Barrett’s Oesophagus https://ClinicalTrials.gov/show/NCT02498041 Completed University of Cambridge 2012-07-31
NCT02484248 Ketotifen for Children With Functional Dyspepsia in Association With Duodenal Eosinophilia https://ClinicalTrials.gov/show/NCT02484248 Recruiting Children’s Mercy Hospital Kansas City 2020-03-31
NCT02481583 Pharmacokinetic Study of Levosulpiride https://ClinicalTrials.gov/show/NCT02481583 Completed Wuhan Union Hospital, China 2013-05-31
NCT02460601 The Efficacy and Safety of Qizhiweitong Granule on Patients With Functional Dyspepsia in a Multi-center Clinical Study https://ClinicalTrials.gov/show/NCT02460601 Completed Wuhan Union Hospital, China 2015-08-31
NCT02389998 Efficacy of Open Label Placebo in Children With FGIDs https://ClinicalTrials.gov/show/NCT02389998 Recruiting Boston Children’s Hospital 2018-12-31
NCT02388269 A Randomized, Single Centre, Double-blind, Parallel, Sham-controlled Pilot Study Using gammaCore®-G https://ClinicalTrials.gov/show/NCT02388269 Completed ElectroCore INC 2015-05-31
NCT02365701 Study of Motilitone to Treat Functional Dyspepsia https://ClinicalTrials.gov/show/NCT02365701 Completed Dong-A ST Co., Ltd. 2018-02-28
NCT02306941 Internet-delivered CBT for Functional Abdominal Pain in Adolescents - a Pilot https://ClinicalTrials.gov/show/NCT02306941 Completed Karolinska Institutet 2016-07-31
NCT02296021 Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Bismuth-containing Quadruple Therapy https://ClinicalTrials.gov/show/NCT02296021 Completed Xijing Hospital of Digestive Diseases 2015-09-30
NCT02277431 Probiotic Supplementation Among Adults With Recurrent Gastrointestinal Symptoms https://ClinicalTrials.gov/show/NCT02277431 Completed University of Maryland, Baltimore 2015-09-30
NCT02197143 A Comparison of Efficacy of Intravenous Esomeprazole and Ranitidine Treatment of Dyspeptic Pain https://ClinicalTrials.gov/show/NCT02197143 Completed Pamukkale University 2014-07-31
NCT02175901 Amoxicillin/Metronidazole Based Quadruple Therapy for Helicobacter Pylori Eradication https://ClinicalTrials.gov/show/NCT02175901 Completed Shanghai Jiao Tong University School of Medicine 2015-01-31
NCT02170870 Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus https://ClinicalTrials.gov/show/NCT02170870 Completed Mayo Clinic 2017-11-17
NCT02153567 SSRI Study for Functional Dyspepsia (SS) https://ClinicalTrials.gov/show/NCT02153567 Completed Chinese University of Hong Kong 2018-12-31
NCT02113605 Cognitive Behavior Therapy (CBT) for Children With Functional Gastrointestinal Disorders https://ClinicalTrials.gov/show/NCT02113605 Completed Karolinska Institutet 2015-11-30
NCT02105090 Efficacy Study of Articaine Lozenge to Enhance the Procedural Compliance of the Adults Undergoing Gastroduodenoscopy https://ClinicalTrials.gov/show/NCT02105090 Recruiting Helsinki University Central Hospital 2019-12-31
NCT01281501 Symptomatic Relief of Acute Dyspeptic Pain in Emergency Department With Pantoprazole https://ClinicalTrials.gov/show/NCT01281501 Completed Chulalongkorn University 2011-10-31
NCT02051348 Study of Pylopass Versus Placebo in Subjects Who Are Helicobacter Pylori Carriers and With Mild Indigestion https://ClinicalTrials.gov/show/NCT02051348 Completed Atlantia Food Clinical Trials 2014-12-31
NCT02037776 The Efficacy and Safety Study of Rikkunshito in Patients With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT02037776 Completed Osaka City University 2016-03-25
NCT03358485 Study of Aolanti Weikang Tablets in Healthy Volunteers https://ClinicalTrials.gov/show/NCT03358485 Completed Jiangxi Qingfeng Pharmaceutical Co. Ltd. 2018-04-21
NCT01980095 ERADICATE Hp - Treating Helicobacter Pylori With RHB-105 https://ClinicalTrials.gov/show/NCT01980095 Completed RedHill Biopharma Limited 2015-06-30
NCT01973790 Phase III, Long-term, Open-label Safety Study of Z-338 https://ClinicalTrials.gov/show/NCT01973790 Completed Zeria Pharmaceutical 2016-11-30
NCT01919021 Assessment of Gastro-Intestinal Function to a Mixed Meal by Non-invasive Imaging https://ClinicalTrials.gov/show/NCT01919021 Completed Nottingham University Hospitals NHS Trust 2014-04-30
NCT01915173 Response to Supplement and Placebo in GERD https://ClinicalTrials.gov/show/NCT01915173 Completed Beth Israel Deaconess Medical Center 2014-04-30
NCT01888237 High Dose PPI Triple Therapy Versus Sequential Therapy for Helicobacter Pylori Eradication https://ClinicalTrials.gov/show/NCT01888237 Completed Mahidol University 2014-08-31
NCT01869491 Compound Sodium Alginate Double Action Chewable Tablet Symptomatic Relief Study https://ClinicalTrials.gov/show/NCT01869491 Completed Reckitt Benckiser Healthcare (UK) Limited 2014-05-31
NCT01851863 Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia https://ClinicalTrials.gov/show/NCT01851863 Completed RenJi Hospital 2014-06-30
NCT01849107 Plasma Citrulline: A Marker for Monitoring & Quantifying Radiation-Induced Small Bowel Toxicity https://ClinicalTrials.gov/show/NCT01849107 Completed Asan Medical Center 2013-12-31
NCT01837940 Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population https://ClinicalTrials.gov/show/NCT01837940 Completed Örebro University, Sweden 2013-09-30
NCT01817465 A Study to Demonstrate the Efficacy and Safety of Motilitone® https://ClinicalTrials.gov/show/NCT01817465 Completed Dong-A ST Co., Ltd. 2014-03-31
NCT01802710 Clinical Improvement and in Quality of Life-Functional Dyspepsia- https://ClinicalTrials.gov/show/NCT01802710 Completed Hospital Galdakao-Usansolo 2012-09-30
NCT01696734 Domperidone in Treating Patients With Gastrointestinal Disorders https://ClinicalTrials.gov/show/NCT01696734 Recruiting M.D. Anderson Cancer Center 2021-10-31
NCT01677715 Study of Yili Mei Yi Tian Active Lactobacillus Drink to Improve Immunity and Digestive System https://ClinicalTrials.gov/show/NCT01677715 Completed Inner Mongolia Yili Industrial Group Co., Ltd 2011-11-30
NCT01671670 Acupuncture for Patients With Function Dyspepsia https://ClinicalTrials.gov/show/NCT01671670 Completed Chengdu University of Traditional Chinese Medicine 2014-06-30
NCT01670552 Evaluation of Two Therapies for the Treatment of Osteoarticular Inflammation in Dyspeptic Patients https://ClinicalTrials.gov/show/NCT01670552 Completed EMS 2016-10-28
NCT01668927 Empirical Rescue Therapies of Helicobacter Pylori Infection https://ClinicalTrials.gov/show/NCT01668927 Completed Shanghai Jiao Tong University School of Medicine 2012-09-30
NCT01667718 Bismuth Improves the Efficacy of Levofloxacin-containing Triple Therapy for Helicobacter Pylori Treatment https://ClinicalTrials.gov/show/NCT01667718 Completed Shanghai Jiao Tong University School of Medicine 2012-10-31
NCT01667692 Aizthromycin or Clarithromycin in H-pylori Eradication Regimen https://ClinicalTrials.gov/show/NCT01667692 Completed Shahid Sadoughi University of Medical Sciences and Health Services 2011-11-30
NCT01667575 Efficiency Study of Clarithromycin and Bismuth-containing Quadruple Therapy to Treat H.Pylori https://ClinicalTrials.gov/show/NCT01667575 Completed Shanghai Jiao Tong University School of Medicine 2013-05-31
NCT01643083 Rifaximin for Functional Dyspepsia https://ClinicalTrials.gov/show/NCT01643083 Completed The University of Hong Kong 2015-05-31
NCT01513785 New Dual Therapy for Primary Treatment of Helicobacter Pylori Infection：a Pilot Study https://ClinicalTrials.gov/show/NCT01513785 Completed Shanghai Jiao Tong University School of Medicine 2011-10-31
NCT01355276 Efficacy and Safety of Cinitapride Tablets in the Treatment of Mild to Moderate Functional Dyspepsia https://ClinicalTrials.gov/show/NCT01355276 Completed Eisai Inc. 2011-06-30
NCT01349413 BRAVO Study for Functional Dyspepsia https://ClinicalTrials.gov/show/NCT01349413 Completed Chinese University of Hong Kong 2017-12-30
NCT04449887 The Role of Intestinal Flora in the Pathogenesis of FD and the Intervention of Xiangsha Liujunzi https://ClinicalTrials.gov/show/NCT04449887 Recruiting Xiyuan Hospital of China Academy of Chinese Medical Sciences 2021-12-01
NCT04429802 The Effect of Prucalopride (Resolor®) on Gastric Motor Function and Gastric Sensitivity https://ClinicalTrials.gov/show/NCT04429802 Completed Universitaire Ziekenhuizen Leuven 2015-06-01
NCT04352062 Melatonin Supplementation in Postmenopausal Women With H. Pylori-associated Dyspepsia https://ClinicalTrials.gov/show/NCT04352062 Completed Medical Universtity of Lodz 2018-10-26
NCT04129762 Effect of a Diet Without Non-caloric Sweeteners on Gastrointestinal Symptoms in Patients With IBS and Dyspepsia https://ClinicalTrials.gov/show/NCT04129762 Recruiting Hospital General de Mexico 2020-08-31
NCT04053049 Advancing Nutritional Science for Children With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT04053049 Recruiting Baylor College of Medicine 2020-12-01
NCT04043208 Treatment of Functional Abdominal Distension https://ClinicalTrials.gov/show/NCT04043208 Recruiting Hospital Universitari Vall d’Hebron Research Institute 2020-06-19
NCT04030780 Effect of Sporebiotics in FD https://ClinicalTrials.gov/show/NCT04030780 Recruiting Universitaire Ziekenhuizen Leuven 2020-07-31
NCT04008901 The Efficacy and Safety of “BST104” (Lonicera Flos Extract) in Mild to Moderate Functional Dyspepsia Subjects https://ClinicalTrials.gov/show/NCT04008901 Completed Seoul National University Bundang Hospital 2018-07-02
NCT03973567 MRI Study of Antidepressants in the Treatment of Refractory Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03973567 Recruiting Second Affiliated Hospital, School of Medicine, Zhejiang University 2019-12-31
NCT03941288 Efficacy and Safety of Cannabidiol for Gastroparesis and Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03941288 Recruiting Mayo Clinic 2024-06-30
NCT03931330 Does Improving Vagal Tone Increase Mitochondrial Bioenergetics https://ClinicalTrials.gov/show/NCT03931330 Completed Medical College of Wisconsin 2019-09-24
NCT03884270 Functional Dyspepsia Hypnosis https://ClinicalTrials.gov/show/NCT03884270 Recruiting Loyola University 2020-12-31
NCT03883464 Quality of Life Related to Digestive Symptoms After Cholecistectomy. Short Term Effects of a Low Fat Intake. https://ClinicalTrials.gov/show/NCT03883464 Completed Consorci Sanitari de Terrassa 2019-03-12
NCT03857425 Helicobacter Pylori Eradication With Clostridum Butyricum Capsule and Bacillus Coagulans Tablets https://ClinicalTrials.gov/show/NCT03857425 Completed Xijing Hospital of Digestive Diseases 2019-08-31
NCT03856294 The Effect of Rikkunshito on Gastric Accommodation and Nutrient Volume Tolerance in Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03856294 Completed Universitaire Ziekenhuizen Leuven 2018-10-31
NCT03844100 Effectiveness and Safety in Administrating CNU® Capsule to Refractory Functional Dyspepsia Patients https://ClinicalTrials.gov/show/NCT03844100 Recruiting Gangnam Severance Hospital 2020-12-30
NCT03865290 Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia https://ClinicalTrials.gov/show/NCT03865290 Recruiting Mayo Clinic 2025-03-31
NCT03652571 Nortriptyline for the Treatment of Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03652571 Recruiting Maastricht University Medical Center 2020-09-01
NCT03635372 A Comparison of Effectiveness of Oral Sucrolfate, Alginate and Hydrotalcide in Dispeptic Pain Treatment https://ClinicalTrials.gov/show/NCT03635372 Completed Pamukkale University 2017-10-22
NCT03625674 Impact of Stigma on Compliance to Medication in Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03625674 Recruiting RenJi Hospital 2020-12-31
NCT03617861 Effect of Secretin in Functional Dyspepsia and Healthy Subjects https://ClinicalTrials.gov/show/NCT03617861 Completed Mayo Clinic 2019-07-01
NCT03603730 Vagal Nerve Stimulation for Functional Dyspepsia and Gastroparesis https://ClinicalTrials.gov/show/NCT03603730 Recruiting Massachusetts General Hospital 2020-09-30
NCT03548363 Effect of Gingest on Symptoms of Dyspepsia https://ClinicalTrials.gov/show/NCT03548363 Completed Atlantia Food Clinical Trials 2019-01-02
NCT03531372 Mipolixin® Compared to Poliprotect® in Moderate Functional Dyspepsia and Heartburn. https://ClinicalTrials.gov/show/NCT03531372 Recruiting Aboca Spa Societa’ Agricola 2020-06-30
NCT03420729 Acceptability and Tolerability of Magnetic Assisted Capsule Endoscopy Compared to Gastroscopy https://ClinicalTrials.gov/show/NCT03420729 Recruiting Sheffield Teaching Hospitals NHS Foundation Trust 2020-03-06
NCT01248221 Carbon-13 (13C)-Spirulina Platensis Gastric Emptying Breath Test (GEBT) https://ClinicalTrials.gov/show/NCT01248221 Completed Mayo Clinic 2011-12-31
NCT01205100 Treatment of Abdominal Distension by Biofeedback - a Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT01205100 Completed Hospital Universitari Vall d’Hebron Research Institute 2016-01-31
NCT01152047 The Effect of Oxytocin on Gastric Emptying https://ClinicalTrials.gov/show/NCT01152047 Completed Skane University Hospital 2015-04-30
NCT01140828 A Study of Rabeprazole for Prevention of Non Steroidal Anti-inflammatory Drug -Associated Gastroduodenal Injury https://ClinicalTrials.gov/show/NCT01140828 Completed Chinese University of Hong Kong 2012-10-31
NCT01089543 A Study of E3810 for Japanese Subjects With Functional Dyspepsia (SAMURAI Study: Suppression of Acid Milieu With Rabeprazole Improving Functional Dyspepsia ) (Study E3810-J081-204) https://ClinicalTrials.gov/show/NCT01089543 Completed Eisai Inc. 2011-08-31
NCT01053871 Propofol Versus Midazolam With Fentanyl for EGD Endomicroscopy https://ClinicalTrials.gov/show/NCT01053871 Completed Shandong University 2010-05-31
NCT01047800 Functional Gastrointestinal Disorder Screening Program - A Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT01047800 Completed Chinese University of Hong Kong 2015-05-31
NCT00996788 Anti Free Radical & Anti Inflammatory Effect & Safety of Rebamipide in Chronic Gastritis https://ClinicalTrials.gov/show/NCT00996788 Completed PT Otsuka Indonesia 2012-01-31
NCT00987805 Efficacy of Banhasasim-tang on Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00987805 Completed Korea Health Industry Development Institute 2011-01-31
NCT00956397 Does Small Intestinal Bacterial Overgrowth Contribute to Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00956397 Completed New Mexico VA Healthcare System 2012-03-31
NCT00951431 Gastric Functions & Proton Pump Inhibitor( PPI) Study https://ClinicalTrials.gov/show/NCT00951431 Completed Chinese University of Hong Kong 2015-12-31
NCT00850746 A Study to Evaluate the Effect of Repeat Oral Doses of YM443 on Cardiac Repolarization in Healthy Adults https://ClinicalTrials.gov/show/NCT00850746 Completed Astellas Pharma Inc 2009-04-30
NCT04350346 The Comparative Analysis Between Motilitone and Gasmotin for the Symptom Relief in Gallstone Patients With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT04350346 Recruiting Yonsei University 2020-08-31
NCT03119766 Clinical Trial of Efficacy and Safety of Kolofort in Functional Dyspepsia Patients https://ClinicalTrials.gov/show/NCT03119766 Completed Materia Medica Holding 2020-01-11
NCT03788109 Relationship Between Gastric Accommodation, TLESRs and Reflux in HV and in GERD With or Without Overlapping Dyspepsia https://ClinicalTrials.gov/show/NCT03788109 Completed Universitaire Ziekenhuizen Leuven 2018-06-15
NCT02551029 fMRI and Visceral Perception Upon Capsaicin Infusion https://ClinicalTrials.gov/show/NCT02551029 Completed Maastricht University Medical Center 2019-07-26
NCT01682798 Study of Yili “Changqing” Pro-ABB Yoghurt in the Improvement of Human Gastrointestinal Tract System https://ClinicalTrials.gov/show/NCT01682798 Completed Inner Mongolia Yili Industrial Group Co., Ltd 2009-06-30
NCT00786214 Treatment of Functional Dyspepsia With Acupuncture https://ClinicalTrials.gov/show/NCT00786214 Completed National University Hospital, Singapore 2009-12-31
NCT00772837 Effect of Eradication of Helicobacter Pylori on the Dyspeptic Symptoms https://ClinicalTrials.gov/show/NCT00772837 Completed Aga Khan University 2008-12-31
NCT00764374 A Long-term, Open-label, Uncontrolled Trial of YM443 (Z-338) in Patients With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00764374 Completed Astellas Pharma Inc 2009-12-31
NCT00761358 To Verify the Efficacy of Z-338 in Subjects With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00761358 Completed Zeria Pharmaceutical 2010-06-30
NCT00723502 Efficacy and Safety Study of Finafloxacin Used in Helicobacter Pylori Infected Patients https://ClinicalTrials.gov/show/NCT00723502 Completed MerLion Pharmaceuticals GmbH 2009-04-30
NCT00693407 Study of Endogenous Inhibitory Modulation During Gastric and Somatic Stimulation https://ClinicalTrials.gov/show/NCT00693407 Completed National University Hospital, Singapore 2011-09-30
NCT02091635 Efficacy of Motilitone on Gastric Accommodation in Healthy Adult Patients: Evaluation Using MRI Method https://ClinicalTrials.gov/show/NCT02091635 Completed Samsung Medical Center 2013-10-31
NCT00663897 Lansoprazole Versus Mosapride for Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00663897 Completed Lotung Poh-Ai Hospital 2009-07-31
NCT00599677 Randomized Controlled Trial of Acupuncture for Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00599677 Completed Chengdu University of Traditional Chinese Medicine 2009-09-30
NCT00521703 Evaluation of Topical Lidocaine Spray as Adjuvant to Upper Gastrointestinal Endoscopy in Children https://ClinicalTrials.gov/show/NCT00521703 Completed Hospital Infantil Cândido Fontoura NA
NCT00458328 The Effect of Z-338 in Subjects With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00458328 Completed Zeria Pharmaceutical 2009-09-30
NCT00404534 Helicobacter Eradication Relief of Dyspeptic Symptoms https://ClinicalTrials.gov/show/NCT00404534 Completed Hospital de Clinicas de Porto Alegre 2009-06-30
NCT00363597 Intestinal Permeability in Children/Adolescents With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00363597 Completed Children’s Mercy Hospital Kansas City 2010-07-31
NCT00358410 An Exploratory Study Examining The Effects Of Taking GW679769 Once-Daily For 4 Days In Patients With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00358410 Completed GlaxoSmithKline 2006-08-31
NCT00333372 To Evaluate the Efficacy of Z-338 in Subjects With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00333372 Completed Zeria Pharmaceutical NA
NCT00328679 Evaluation of Food Hypersensitivity in Children/Adolescents With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00328679 Completed Children’s Mercy Hospital Kansas City 2008-09-30
NCT00323817 To Evaluate the Efficacy and Safety in Subjects With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00323817 Completed Zeria Pharmaceutical 2009-04-30
NCT00303264 The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia. https://ClinicalTrials.gov/show/NCT00303264 Completed Forest Laboratories 2007-08-31
NCT00298194 The Effects of Z-338 in Subjects With and Without Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00298194 Completed Zeria Pharmaceutical 2008-07-31
NCT00296582 Gastric Motor Function Measurement in Dyspepsia and Normal Subjects https://ClinicalTrials.gov/show/NCT00296582 Completed Mayo Clinic 2007-06-30
NCT00292578 NAET® Testing Devices in Detection of Hypersensitivity to Cane Sugar https://ClinicalTrials.gov/show/NCT00292578 Completed Nambudripad’s Allergy Research Foundation NA
NCT00275743 Use of MRI for Assessing Stomach Relaxation in Response to a Meal https://ClinicalTrials.gov/show/NCT00275743 Completed Mayo Clinic 2008-12-31
NCT00272103 Itopride in Functional Dyspepsia:a Dose Finding Study https://ClinicalTrials.gov/show/NCT00272103 Completed Royal Adelaide Hospital NA
NCT00251992 Nexium Dyspepsia/AST https://ClinicalTrials.gov/show/NCT00251992 Completed AstraZeneca 2005-01-31
NCT00251914 Nexium Dyspepsia/AST https://ClinicalTrials.gov/show/NCT00251914 Completed AstraZeneca 2005-01-31
NCT00248651 Functional Dyspepsia Treatment Trial https://ClinicalTrials.gov/show/NCT00248651 Completed Mayo Clinic 2013-07-31
NCT00247715 Comparison of a “Step-Up” Versus a “Step-Down” Treatment Strategy for Patients With New Onset Dyspepsia in General Practice (The DIAMOND-Study) https://ClinicalTrials.gov/show/NCT00247715 Completed Radboud University NA
NCT00243724 HEARD (Long Term) Study - Histology of the Esophagus in Acid-Related Disease https://ClinicalTrials.gov/show/NCT00243724 Completed AstraZeneca 2007-06-30
NCT00232102 Extension Study to Assess the Long-Term Safety of Tegaserod in Women With Symptoms of Dyspepsia https://ClinicalTrials.gov/show/NCT00232102 Completed Novartis NA
NCT00232089 Assessment of Efficacy and Safety of Tegaserod Treatment and Placebo in Women With Dyspepsia https://ClinicalTrials.gov/show/NCT00232089 Completed Novartis 2006-06-30
NCT00232037 Extension Study to Assess the Long-Term Safety of Tegaserod in Women With Symptoms of Dyspepsia https://ClinicalTrials.gov/show/NCT00232037 Completed Novartis NA
NCT00232024 Assessment of Efficacy and Safety of Tegaserod Treatment and Placebo in Women With Dyspepsia https://ClinicalTrials.gov/show/NCT00232024 Completed Novartis NA
NCT00222131 Inhibition of Gastric Acid is the Key to Satisfactory Relief of Symptoms With Esomeprazole in NUD Patients https://ClinicalTrials.gov/show/NCT00222131 Completed University of Kansas Medical Center 2008-01-31
NCT00217347 Evaluation of Efficiency of Esophageal Capsule Endoscopy in the Screening of Patients With Gastroesophageal Reflux Disease or Dyspepsia as Compared to Upper Endoscopy https://ClinicalTrials.gov/show/NCT00217347 Completed Nantes University Hospital NA
NCT00173953 Lymphocytic Subsets and Cytokine Production With H. Pylori Infection https://ClinicalTrials.gov/show/NCT00173953 Completed National Taiwan University Hospital NA
NCT00171470 The Role of Tegaserod Therapy in the Management of Dyspeptic Symptoms in Female Patients on Proton Pump Inhibitors for the Treatment of Heartburn. https://ClinicalTrials.gov/show/NCT00171470 Completed Novartis NA
NCT00171457 The Effects of Tegaserod on Mechanical Sensitivity of the Esophagus and Stomach in Patients With Heartburn and Dyspepsia. https://ClinicalTrials.gov/show/NCT00171457 Completed Novartis NA
NCT00164996 Ultrathin Versus Conventional Esophagogastroduodenoscopy in Unsedated Patient With or Without Local Pharyngeal Anaesthesia https://ClinicalTrials.gov/show/NCT00164996 Completed Chinese University of Hong Kong 2010-09-30
NCT00164775 The Efficacy of Imipramine in Treatment of Refractory Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00164775 Completed Chinese University of Hong Kong 2010-08-31
NCT00148603 Montelukast in the Treatment of Duodenal Eosinophilia https://ClinicalTrials.gov/show/NCT00148603 Completed Children’s Mercy Hospital Kansas City NA
NCT00132171 Helicobacter Pylori Eradication With a New Sequential Treatment https://ClinicalTrials.gov/show/NCT00132171 Completed St. Orsola Hospital NA
NCT00120315 Proton Pump Inhibitor Treatment Stop https://ClinicalTrials.gov/show/NCT00120315 Completed Odense University Hospital 2007-03-31
NCT00115362 Serotonin Effect in Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00115362 Completed Radboud University NA
NCT00112333 Defining Central Circuits of Pain https://ClinicalTrials.gov/show/NCT00112333 Completed Massachusetts General Hospital 2011-02-28
NCT00112203 Long-Term Safety and Efficacy of Itopride Hydrochloride (HCl) in Patients Suffering From Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00112203 Completed Forest Laboratories 2006-07-31
NCT00112190 Effect of Itopride, on Symptoms of Functional Dyspepsia, Such as Indigestion, Bloating, Inability to Finish a Meal https://ClinicalTrials.gov/show/NCT00112190 Completed Forest Laboratories 2005-03-31
NCT00112177 Effect of Itopride, on Symptoms of Functional Dyspepsia, Such as Indigestion, Bloating, Inability to Finish a Meal https://ClinicalTrials.gov/show/NCT00112177 Completed Forest Laboratories 2006-08-31
NCT00110968 Long-term Safety and Efficacy of Itopride Hydrochloride (HCl) in Patients Suffering From Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00110968 Completed Forest Laboratories 2006-07-31
NCT00102310 YM443 in Subjects With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT00102310 Completed Astellas Pharma Inc 2006-03-11

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03321383 Health Related Quality of Life in Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03321383 Completed Indonesia University 2017-06-30
NCT03076411 Pepsin in Patients With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT03076411 Completed Nordmark Arzneimittel GmbH & Co. KG 2013-12-19
NCT02425553 Effects of Diet on Reflux and Dyspepsia https://ClinicalTrials.gov/show/NCT02425553 Completed University of Zurich 2015-04-30
NCT02360696 Functional Dyspepsia (FD) - Clinical Response to Montelukast in Children https://ClinicalTrials.gov/show/NCT02360696 Completed Children’s Mercy Hospital Kansas City 2016-08-31
NCT02340312 Functional Dyspepsia Microbiome Study https://ClinicalTrials.gov/show/NCT02340312 Completed Children’s Mercy Hospital Kansas City 2018-09-30
NCT02320981 Mucosal Impedance in Pediatric Population https://ClinicalTrials.gov/show/NCT02320981 Completed Vanderbilt University Medical Center 2016-09-30
NCT02173925 Gut Hormone, Nociceptors, Neurotrophic Factors Expression in Functional Dyspepsia https://ClinicalTrials.gov/show/NCT02173925 Completed Seoul National University Bundang Hospital 2014-06-30
NCT02113527 Gastric Activity and Gastrointestinal Peptides in Patients With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT02113527 Completed Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis 2014-11-30
NCT01990339 Lansoprazole Tablets Special Drug Use Surveillance Gastroesophageal Reflux Disease With Dyspepsia Symptoms https://ClinicalTrials.gov/show/NCT01990339 Completed Takeda 2010-12-31
NCT04153552 Upset Stomach Relief for Mild and Moderate Indigestion and Heartburn https://ClinicalTrials.gov/show/NCT04153552 Active, not recruiting Hawthorne Effect Inc. 2020-08-18
NCT01591174 Ghrelin and Gastric Emptying in Children With Functional Dyspepsia https://ClinicalTrials.gov/show/NCT01591174 Completed Children’s Mercy Hospital Kansas City 2016-04-22
NCT01382667 Plasma Levels of Glucagon-like Peptide-2 and Dyspepsia in Patients With Extraintestinal Cancer During Chemotherapy https://ClinicalTrials.gov/show/NCT01382667 Completed Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis 2011-12-31
NCT04294823 Sensitivity and Specificity of the Modified Helicobacter Test INFAI https://ClinicalTrials.gov/show/NCT04294823 Recruiting International Pharmaceutical Consultancy 2021-01-31
NCT04279990 Assessment of Gastric Motility on Funtional Dyspepsia and Joint Hypermobility Syndrome https://ClinicalTrials.gov/show/NCT04279990 Completed Universitaire Ziekenhuizen Leuven 2016-11-01
NCT00920400 Diagnostic Value of Fecal Calprotectin in Disorders of the Upper Gastrointestinal Tract https://ClinicalTrials.gov/show/NCT00920400 Completed University Hospital, Basel, Switzerland 2009-09-30
NCT00275795 NAET Screening for Food Allergy, Sensitivity and Intolerances Using IgE-Specific Antigen Test and NST- NAET® https://ClinicalTrials.gov/show/NCT00275795 Completed Nambudripad’s Allergy Research Foundation NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT01822470 Small Intestinal Bacterial Overgrowth: A Prospective Registry https://ClinicalTrials.gov/show/NCT01822470 Recruiting Indiana University 2020-12-31
NCT03868267 Japanese Upper GI Symptoms Compared With Iranian and Canadian Patients Presenting https://ClinicalTrials.gov/show/NCT03868267 Recruiting Hamilton Health Sciences Corporation 2021-02-28